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Fecal Matter Transplant for C Diff

Clostridium difficile or C. diff is a bacteria that causes recurring and severe diarrhea, nausea and fever. Those infected with C. diff have usually been taking antibiotics for other infections. While antibiotics help fight bad bacteria, they can also kill good bacteria. When this happens, C. diff can grow and cause life threatening diarrhea and inflammation of the colon.

If you’ve been diagnosed with C. diff and it returns after rounds of antibiotics to treat it, your gastroenterologist may recommend a fecal matter transplant. To be eligible for a FMT, you must have had three different C. diff infections that resisted antibiotic treatment.

Preparing for a FMT is similar to preparing for a colonoscopy. Those on antibiotics must stop taking them 48 hours before the procedure. An anti-diarrhea medication is administered a few hours before the procedure. While under anesthesia, stool from a healthy donor is infused into your colon with a colonoscope, the same device used in a colonoscopy. The healthy stool will transfer beneficial, balanced bacteria to your colon, restoring the compromised stool and stopping the recurrence of C. diff.

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